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May 8, - How do Pepcid AC, Zantac and other antihistamines stop Asian .. there's an increased level of alcohol in your body, and you can get drunk as. Dec 10, - We've all heard of Asian glow—the telltale facial flush that often occurs When that happens, you essentially become drunk, with symptoms like Zantac and Pepcid AC, both histamine blockers, to prevent flushing. In other words, antihistamines increase the rate at which blood alcohol levels rise, and.